Integrating Special Populations

ITS investigators have access to a diverse pool of patients that visit UTMB clinics from Galveston/Houston and surrounding areas for a variety of health care needs. The Shriners Burns Institute predominantly sees pediatric patients with severe burn injuries and, in collaboration with the ITS, is testing interventions in these patients through a Multidisciplinary Translational Team (MTT) model. Through the Sealy Center on Aging, a large cohort of elderly population is available to investigators interested in studying the phenomenon of aging and geriatric diseases. Other patient populations being studied as part of a MTT include patients with severe asthma, respiratory infections such as otitis media, obesity, women’s health issues, colorectal cancer, hepatocellular cancer, addiction, and parasitic infections.

The UTMB CTSA hub supports active MTTs conducting applied research in special populations (SP) across the lifespan from in utero, pediatric to aging populations using Phase I-III CTs including RCTs, pragmatic CTs and separately, patient-centered outcomes (PCOR) approaches. 

Our prestigious Claude D. Pepper Older Independence Center in Aging has pioneered nutritional supplementation CTs to prevent sarcopenia of aging and is a recruitment site for a multi-site PCOR/NIA-funded STRIDE study with 8 other sites in the CTSA consortium.

Our internationally recognized pediatric burns MTT and maternal fetal medicine/pharmacology that have resulted in FDA IND approvals for treatment of the burn hypermetabolic state and pregnancy-associated hypertension. 

The UTMB CTSA is a site for the NCATS/Rare Disease Collaborative Network (RDCRN) in the Porphyria Consortium developing first-in-class drug for increasing sunlight tolerance.