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About the Informatics Core

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ITS Informatics Service Center

The goal of the Institute for Translational Sciences Informatics Core (ITSIC) is to expand Health Informatics and Bioinformatics technology utilization by scientists performing clinical and basic science research. The Institute for Translational Sciences will provide the technical framework and administrative infrastructure to effectively drive innovation for Informatics at UTMB and with our collaborative partners.

The Informatics Core supports UTMB investigators on projects in the health informatics and the bioinformatics domains. Selected faculty from ITS/Health Informatics, BMB and PMCH provide offer a number of services to UTMB researchers, students, and administrative personnel.  You can submit a request for services at https://utmb.us/2ae or by sending email to the ITS Informatics Core

Informatics Core Services
We consult and advise on a variety of biomedical informatics projects. With a spectrum of expertise in bioinformatics, translational informatics and health informatics, we aim to bring you concierge service. Below is a sample of services which we currently offer. If you are interested in any information or data services for your research project (even if not listed below), please contact us for help at the Informatics Core.

Bioinformatics

  • NGS processing (also other platforms: microarray, proteomics)
  • Developing and maintaining analysis pipelines for translational or basic research
  • Functional analysis of NGS results and other datasets
  • Cross-platform integration
    • Integration of SNP / polymorphism data
    • Integration with new genomics tools (epigenetics, chromatin structure)
    • Identification of relevant data in public repositories
    • Normalization of diverse datasets
    • Data formatting and updates (liftOver and similar to relate new to existing results)
  • Quantitative model building /  Advanced statistical analysis of data
  • Significance testing through randomization / numerical simulations
  • Data-driven generation and assessment of hypotheses
  • Preparing methods section for publications
  • Data formatting, filtering, preparing tables, graphs, illustrations
  • Computational assistance with experimental design
    • sequence retrieval
    • automation / primer design / etc
  • Ingenuity Pathways Analysis (IPA)

Translational/Health Informatics

  • Clinical trial feasibility studies
  • EMR data for retrospective studies and clinical trials
  • Clinical data capture/forms (REDCap)
  • UTMB Discover application
  • Bio-banking platform to collect, store, process, annotate and distribute bio-specimens

Common Services

  • Front-end web design and maintenance using Sitefinity and other tools
  • Visual Analytics: identification of patterns in large datasets
  • Machine learning: developing models
  • Database design and hosting
  • Grant Preparation (data processing / data dissemination consulting and narratives)

Education

  • Informatics-related courses
  • Workshops
  • Customized training of staff / students

 


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