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i2b2 (Informatics for Integrating Biology and the Bedside) is an open source application which enables clinical researchers to use existing clinical data for discovery research. This platform enjoys wide international adoption by the CTSA network, academic health centers, and industry. Specific uses include: Identifying a population for clinical trials, Identifying geographic areas for clinical trial recruitment, Quick "what if's" - for example where you are trying to link a drug to a procedure or diagnosis, Eliminate manual chart reviews for many data request types - resulting in increased efficiency and data accuracy, Provides the base structure to allow for future expansion into federated queries for discovery research across multiple institutions.
i2b2 is designed to enable clinical researchers to accelerate the translation of genomic and “traditional” clinical findings into novel diagnostics, prognostics, and therapeutics. Conversely, it provides a collaborative organizational and software infrastructure to allow basic researchers to leverage insights arising from clinical studies.